METABOLISM

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Interaction of compounds with co administered drugs is a concern. These drug-drug interactions result in different pharmacokinetic profiles and may lead to an adverse event or loss of efficacy for either the candidate or the marketed drugs.

Cytovier offers a range of services to evaluate the potential for drug-drug interactions, including cytochrome P450 (CYP450) inhibition, induction and reaction phenotyping.

NON-CYP MEDIATED METABOLISM assays are also offered to customers.